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Mentors and Regional Facilitators
Name Region Skills Interests
Devin Bayly ACCESS CSSN, Campus Champions, CCMNet
Michael Blackmon Campus Champions, ACCESS CSSN
Cody Stevens Campus Champions, CCMNet
Bala Desinghu ACCESS CSSN, Campus Champions, CAREERS, Northeast
Deborah Penchoff Campus Champions
David Liu CCMNet
Elie Alhajjar ACCESS CSSN, CCMNet
Yu-Chieh Chi Campus Champions
Jordan Hayes Campus Champions
Jeffrey Weekley Campus Champions
Jason Wells ACCESS CSSN, Campus Champions
Od Odbadrakh ACCESS CSSN
Kenneth Bundy CAREERS
shuai liu ACCESS CSSN
Mohsen Ahmadkhani CCMNet, ACCESS CSSN
Michael Puerrer Campus Champions, Northeast
Maryam Taeb
Dr. Nabeel Alzahrani Campus Champions, CCMNet
Nannan Shan CCMNet, ACCESS CSSN
Paul Rulis Campus Champions
Rebecca Belshe Campus Champions, CCMNet
Russell Hofmann ACCESS CSSN, CCMNet
Xiaoqin Huang ACCESS CSSN
Swabir Silayi ACCESS CSSN, CCMNet, Campus Champions
Simon Delattre
Soham Pal ACCESS CSSN, Campus Champions, CCMNet
Sathish Srinivasan ACCESS CSSN
William Lai ACCESS CSSN

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Knowledge Base Resources

Title Category Tags Skill Level
Attention, Transformers, and LLMs: a hands-on introduction in Pytorch Learning ai, deep-learning, machine-learning, neural-networks, pytorch Intermediate
DeepChem Tool pytorch, tensorflow, computational-chemistry Beginner, Intermediate, Advanced
fast.ai Website ai, machine-learning, pytorch, training Beginner, Intermediate, Advanced

Engagements

Re-engineering Lilly’s KisunlaTM into a novel antibody targeting IL13RA2 against GBM using AI-driven macromolecular modeling
Atrium Health Levine Cancer
  • Summary and objectives of the proposed experiments: 
  1. An initial research-based Ab (scFv47, discovered by our collaborator Dr. Balyasnikova) model, modeling Ab-Ag (IL13RA2 against GBM) protein complex, and identifying the binding sites (epitopes) using ROSETTA and AlphaFold2 multimer tools.
  2. Graft the CDRs of scFv (single-chain variable fragment) of antibody or Bispecific T cell engagers (BTEs) onto the template Ab, the framework of Lilly's Kisunla™ Ab drug.
  3. Modify, improve, and optimize the overall or full antibody protein structures using AI-driven macromolecule modeling (AlphaFold3).
  4. Explore single nucleotide polymorphism (SNP), pathogenic genetic variants and N-glycosylation of IL13RA2 (target) protein domain interacting with the Ab candidates among the patient population using ROSETTA software packages.
Status: In Progress

People with Expertise

Madhukara Kekulandara

University of Rhode Island

Programs

CAREERS

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student-facilitator

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Xilin Qiao

Programs

ACCESS CSSN

Roles

student-facilitator

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Emanuela Riglioni

Programs

ACCESS CSSN

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student-facilitator

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Expertise

People with Interest

Widodo Samyono

Jarvis Christian College

Programs

Campus Champions, CCMNet

Roles

researcher/educator, research computing facilitator, CCMNet

Widodo Samyono, PhD in Computational and Applied Mathematics

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Matt Ferguson

Boise State University

Programs

At-Large

Roles

researcher/educator, cssn

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Youngsu Kim

California State University-San Bernardino

Programs

ACCESS CSSN

Roles

cssn, CIP

my_pic

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